whatt is naked circular DNA?
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Gene transfer by the uptake of unprotected or “naked” DNA is known as transformation. Naked DNA refers to DNA that is not associated with proteins, lipids, or any other molecule to help protect it. Naked DNA is the result of release of genetic information into the surrounding environment, such as from bursting cells.
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The naked DNA is called plasmid DNA and denoted as pDNA. It is a circular DNA comprises several important DNA sequences needed to integrate GOI into the host genome. There are three major components of gene therapy: The gene of interest, a vector and a target site
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