Biology, asked by tushilsahu123, 2 months ago

Where does glycolysis occur in a cell? Describe the sequence of reaction in it.​

Answers

Answered by mnavneet425
0

Answer:

It occurs in cytoplasm of the cell. Sequence of reactions is Glycolysis: Step 1: The enzyme hexokinase phosphorylates (adds a phosphate group to) glucose in the cell's cytoplasm. In the process, a phosphate group from ATP is transferred to glucose producing glucose 6-phosphate.

Answered by swetharamesh62
0

Answer:

Glycolysis: Glycolysis means "the splitting of sugar". A glucose molecule is converted into 2 molecules of pyruvic acid during glycolysis. It occurs in cytoplasm of the cell.

Sequence of reactions is Glycolysis:

Step 1:

The enzyme hexokinase phosphorylates (adds a phosphate group to) glucose in the cell's cytoplasm. In the process, a phosphate group from ATP is transferred to glucose producing glucose 6-phosphate. Glucose + ATP →hexokinase→hexokinase Glucose - 6 - phosphate + ADP

Step 2: The enzyme phosphohexo seisomerase converts glucose 6-phosphate into its isomer fructose 6-phosphate. Glucose - 6 - phosphate →Phosphohexoseisomerase→Phosphohexoseisomerase Fructose - 6 - phosphate

Step 3: The enzyme phosphofructokinase uses another ATP molecule to transfer a phosphate group to from fructose 1, 6-phosphate.

Step 4: The enzyme aldolase splits fructose 1, 6 bisphosphate into two sugars that are isomers of each other. These two sugars are dihydroxyacetone phosphate and glyceraldehyde phosphate. Fructose 1, 6 bisphosphate →Aldolase→Aldolase Glyceraldehyde 3- Phosphate (GAP) + Dihydroxyacetone 3-phosphate

Step 5: The enzyme triose phosphate isomerase rapidly inter-converts the molecules dihydroxyacetone phosphate into glyceraldehyde 3-phosphate. Glyceraldehyde 3-phosphate is removed as soon as it is formed to be used in the next step of glycolysis. Dihydroxyacetone 3-phosphate →Triosephosphateisomerase→Triosephosphateisomerase Glyceraldehyde 3 phosphate Net result for steps 4 and 5 : Fructose 1, 6-bisphosphate (C6H14O12P2) →→ 2 molecules of glyceraldehyde 3-phosphate (C3H7O6P)

Step 6:The enzyme triose phosphate dehydrogenase serves two functions in this step. First the enzyme transfers a hydrogen (H- ) from glyceraldehyde phosphate to the oxidizing agent nicotinamide adenine dinucleotide (NAD+) to form NADH. Next triose phosphate dehydrogenase adds a phosphate (P) from the cytosol to the oxidized glyceraldehyde phosphate to form 1, 3-bisphosphoglycerate. This occurs for both molecules of glyceraldehyde 3-phosphate produced in step 5. Glyceraldehyde 3-phosphate + H3PO4 + NAD+ →→ 1,3 bisphospho glycerate + NADH + H+

Step 7: The enzyme phosphoglycerokinase transfers a P from 1,3-bisphosphoglycerate to a molecule of ADP to form ATP This happens for each molecule of 1,3-bisphosphoglycerate. The process yields two 3-phosphoglycerate molecules and two ATP molecules.

Step 8: The enzyme phosphoglyceromutase relocates the P from 3-phosphoglycerate from the third carbon to the second carbon to form 2-phosphoglycerate. 3-phosphoglycerate →Phosphoglyceromutase→Phosphoglyceromutase 2

Step 9: The enzyme enolase removes a molecule of water from 2- phosphoglycerate to form phosphoenolpyruvate (PEP). This happens for each molecule of 2-phosphoglycerate →Enolase→Enolase phosphoenol pyruvate + H2O.

Step 10: The enzyme pyruvate kinase transfers a P from PEP to ADP to form pyruvate and ATP. This happens for each molecule of phosphoenolpyruvate + pyruvate kinase+2 ADP2 molecules of pyruvate +2ATP.

End products are 2 pyruvate molecules and 2 ATP molecules.

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