which enzyme contains zinc in active site
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The first zinc metalloenzyme, carbonic anhydrase II (CA3 II, EC 4.2. 1.1), was discovered in 1940 by Keilin and Mann. Since then, > 300 zinc enzymes covering all six classes of enzymes and in different species of all phyla have been discovered (Christianson 1991, Coleman 1992, Vallee and Auld 1990a).
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