Question

Which g protein increases adenylyl cyclase activity?

Answer 1

Answer:

G protein–coupled receptors regulate membrane adenylyl cyclases via direct interaction with the alpha subunits of heterotrimeric G proteins, although in some cases the Gβγ subunits can also activate adenylyl cyclases. Gα subunits are comprised of two domains, a GTPase and an alpha-helical region

JAI SHRI RAM

Answer 2

Both β1- and β2-adrenergic receptors are coupled to G proteins (Gs), which activate adenylyl cyclase. In contrast, α1 and α2 receptors are coupled to two other G proteins, Gq and Gi, respectively. Gi inhibits adenylyl cyclase, and Gq stimulates phospholipase C to generate IP3 and DAG as second messengers.