which of human disorder of blood is control by incomplete allele
Answers
A genetic disease is due to a faulty gene or group of genes. While not all gene defects cause disease, many do. New genetic diseases are discovered every month; as of 2001, there are estimated to be approximately 1,100 genetic diseases.
How Gene Defects Cause Disease
A gene is a recipe for making a protein . Proteins control cell functions, and defects in the instructions for making a protein can prevent the cell from functioning properly. Genes are made of deoxyribonucleic acid (DNA), a chemical composed of units called nucleotides , and are carried on chromosomes within the cell nucleus . Most genes are present in pairs (corresponding to the two sets of chromosomes inherited from one's parents). As well as coding for proteins, genes are the hereditary material. Therefore, genetic diseases can be inherited.
Genetic defects cause diseases in a variety of ways. The simplest way is through a "loss-of-function" mutation. In this type of defect, a change in the DNA nucleotides prevents the gene from making protein, or prevents the protein from functioning once it is made. Genetic diseases due to loss-of-function mutations are very common, and include cystic fibrosis (which affects the lungs and pancreas), Duchenne muscular dystrophy, and the hemophilias, a group of blood-clotting disorders.