Question

Which of the following statement is NOT true?

1.HMP shunt stands for hexose monophosphate shunt

2.HMP shunt does not generate CO2

3.HMP does not generate ATP

4. Pentose phosphate pathway takes place in cytosol​

Answer 1

Answer:

HMP does not generate ATP

Answer 2

HMP shunt does not generate CO2 is not true. (option 2)

• Glucose-6-phosphate has many catabolic fates other than pyruvate (glycolysis).
• Its oxidation can initiate the formation of pentose phosphates via the HMP shunt or pentose phosphate pathway also known as the phosphogluconate pathway or hexose monophosphate pathway.
• (Note:HMP shunt can be classified into oxidative and non-oxidative phases).
• The oxidative fates of one HMP shunt include pentose phosphate (ribose-5-phosphate) and two molecules of NADPH along with the emission of one CO2 molecule.
• There's no consumption or production of ATP involved in the shunt.
• Hence, Option 2 is correct.