Question

Which of the following statements about ddntps is true?
A) They have a hydrogen at the 3’ carbon of the sugar. B) DNA polymerase can add a new dNTP to a 3’ ddNTP. C) They have a free 3’-hydroxyl group on the ribose sugar. D) They have an oxygen at the 2’ carbon of the ribose sugar.

Answer 1

Question :

• Which of the following statements about ddntps is true ?

Solution :

• They have a hydrogen at the 3’ carbon of the sugar.

• DNA polymerase can add a new dNTP to a 3’ ddNTP.

• They have a free 3’-hydroxyl group on the ribose sugar.

• They have an oxygen at the 2’ carbon of the ribose sugar.

Answer 2

Answer:

A) They have a hydrogen at the 3’ carbon of the sugar.

Explanation:

ddNTPs - Dideoxynucleotides and abbreviated as ddNTPs.   They are chain-elongating inhibitors of DNA polymerase, used in the Sanger method for DNA sequencing.   They have a hydrogen at the 3’ carbon of the ribose sugar.

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