Which oxidation state of fe in the heme of hemoglobin is capable of binding oxygen?
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✔✔ When the iron atom in the heme group becomes oxidized (loses an electron), its valence state changes from +2 (ferrous) to +3 (ferric).
✔✔ The hemoglobin is then called methemoglobin (metHb) or ferrihemoglobin (Fe+3 will not bind oxygen). Ordinarily, about 1% of the hemoglobin in a red blood cell is in this form.
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