Question

While much has been reported on c. Difficile pathogenesis in terms of the toxins it produces [5][7], relatively little is known about the interaction of the pathogen with the mammalian gut.

Answer 1

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Clostridium difficile, or C. difficile (a gram-positive anaerobic bacterium), is now recognized as the major causative agent of colitis (inflammation of the colon) and diarrhea that may occur following antibiotic intake. C. difficile infection represents one of the most common hospital infections around the world.
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