who discovered the vaccine for the first time and which disease ? discuss the principal of vaccination
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Edward Jenner in 1796 discovered the vaccine for the first time for tthe disease Smallpox vaccine,
The principle of vaccination is based on the property of ‘memory’ of immune system.
In vaccination, a preparation of antigenic proteins or inactivated/live but weakened pathogen is introduced into the body.
The antigens generate primary immune response by producing antibodies along with memory B-cells and T-cells. When the vaccinated person is attacked by the same pathogens, the existing memory B-cells and T-cells recognise the antigen and overwhelm the invaders with massive production of lymphocytes and antibodies. Hepatitis-B vaccine is produced from yeast
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