Why 2 hrs in acidic medium for gastro resistant tablets?
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An enteric coating is a polymer barrier applied on oral medication that prevents its dissolution or disintegration in the gastric environment.This helps by either protecting drugs from the acidity of the stomach, the stomach from the detrimental effects of the drug, or to release the drug after the stomach (usually in the upper tract of the intestine).Some drugs are unstable at the acid gastric pH, and need to be protected from degradation. Enteric coating is also an effective method to obtain drug targeting (such as gastro-resistant drugs).
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