Question

Why agglutination occurs? No copied answer please ​

Answer 1

Answer: Agglutination occurs because whenever an antigen is mixed with its corresponding antibody called isoagglutinin, the antibody or other molecule binds multiple particles and joins them, creating a large complex.

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Answer 2

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Agglutination is an Antigen - Antibody reaction, in which a particulate antigen combines with it's antibodies in presence of required electrolytes (at Optimum Temperature) leading to visible clumping of particles.

The main theory that describes agglutination is Lattice Formation Theory .

• Equal proportions of antigen and antibody has to be present for Lattice Formation to take place.
• Once lattice formation occurs , visible clumping takes place

If excess antigen or antibody is present , proper lattice formation doesn't occur . This leads to improper Antigen-Antibody Reaction and agglutination fails.