Question

Why checkpoint is required for prevention of cancer?​

Answer 1

Héý māťè hèřě īş ýøůř åñ§wëř.....

Inhibiting the checkpoint allows entry to mitosis despite the presence of DNA damage and can lead to cell death. Importantly, as cancer cells exhibit increased levels of endogenous DNA damage due to an excessive replication stress, inhibiting the checkpoint kinases alone could act as a directed anti-cancer therapy......