Question

why dna replication does not occur in intermitotic interphase

Answer 1

In the myxomycete, Physarum polycephalum, the bulk of nuclear DNA replication occurs  during a period of a few hours immediately following upon mitosis . During the remainder  of the inter mitotic period, incorporation of thymidine- 3 H continues at a low rate in the  region of the nucleolus (radio autographs) . A few nuclei incorporated thymidine-3 H into  the extra nucleolar chromatin at a high rate at all times of the inter mitotic period . These  nuclei were exceptionally large and they frequently contained several small nucleoli of  different sizes rather than the one, central nucleolus which is characteristic of a normal  interphase nucleus.

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