Why does lack of oxygen lead to lactic acid accumulation?
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Muscle fatigue is the result of anaerobic respiration in the muscle cells. The lack of oxygen in muscles makes them use anaerobic respiration. Glucose is broken down to lactic acid and releases much less energy. The build up of lactic acid in the muscles causes pain and stiffness.
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Accumulation of lactic acid in muscles in the absence of oxygen may leads to muscle cramps
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