why entri coated tablets are does not permit the acid medium?
Answers
Answer:
It's enteric and not entri
Explanation:
Enteric Coating
Enteric coating is a useful strategy for the oral delivery of drugs like insulin which rapidly degrade in the stomach, as it prevents the drug being released in the acidic conditions of the stomach before reaching the intestine.
Explanation:
An enteric coating is a polymer barrier applied on oral medication that prevents its dissolution or disintegration in the gastric environment.[1] This helps by either protecting drugs from the acidity of the stomach, the stomach from the detrimental effects of the drug, or to release the drug after the stomach (usually in the upper tract of the intestine).[2] Some drugs are unstable at the pH of gastric acid, and need to be protected from degradation. Enteric coating is also an effective method to obtain drug targeting (such as gastro-resistant drugs). Other drugs such as some anthelmintics may need to reach a high concentration in a specific part of the intestine.[1] Enteric coating may also be used during studies as a research tool to determine drug absorption.[3] Enteric coated medications pertain to the "delayed action" dosage form category. From a pharmacological point of view the term "enteric coating" is not entirely correct, as gastric resistance can be also obtained by adding enteric polymeric systems to the matrix of the dosage form.[citation needed] Tablets, mini-tablets, pellets and granules (usually filled into capsule shells) are the most common enteric-coated dosage forms.[3]