Question

Why gram negetive bacteria are resistant to antibiotic

Answer 1

Answer:Resistance against antibiotics has no relationship with the cell wall thickness but some exeption is there in the case of antibiotics that act on cell wall.

Such antibiotics requires the need of cell wall to alter its production thus affecting it's multiplication.

That is the reason why penicillins don't affect mycoplasma (don't have cell wall)

All other antibiotic resistance origins due to alterations in the genetic make up of the organism due to mutations and other such gene altering processes.

Answer 2

Gram-negative bacteria are more resistant to antibodies and antibiotics than Gram-positive bacteria, because they have a largely impermeable cell wall.