Question

Why is dna ligase popularly called the molecular glue?

Answer 1

DNA fragments with either sticky ends or blunt ends can be inserted into vector DNAwith the aid of DNA ligases. During normal DNA replication, DNA ligase catalyzes the end-to-end joining (ligation) of short fragments of DNA, called Okazaki fragments. ...DNA ligase can then repair these nicks to form an intact duplex.

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Answer 2

DNA fragments with either sticky ends or blunt ends can be inserted into vector DNA with the aid of DNA ligases. During normal DNA replication, DNA ligase catalyzes the end-to-end joining (ligation) of short fragments of DNA, called Okazaki fragments. ... DNA ligase can then repair these nicks to form an intact duplex.