why is the ratio in pleiotrophy 2:1 ? explain it with example.
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For example, Marriage between two carriers of Sickle cell will produce normal, carriers and sickle-cell anaemic children in a 1: 2: 1 ratio. Sickle cell anemic dies and we have only carriers and normals in the ratio of 2: 1. Thus, pleiotropy shows 2:1 ratio.
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