Chemistry, asked by 2025vijaymahariya, 10 hours ago

Why is the solvent in a Williamson Ether Synthesis normally the conjugate acid of the alkoxide?​

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Answered by Anonymous
5

Answer:

Ethers can be synthesized in standard SN2 conditions by coupling an alkoxide with a haloalkane/sulfonate ester. The alcohol that supplies the electron rich alkoxide can be used as the solvent, as well as dimethyl sulfoxide (DMSO) or hexamethylphosphoric triamide (HMPA).

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