Why neutrophils effective against bacterial infection?
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Listeria monocytogenes. ... This indirect infection via cell-to-cell spread is effective, particularly in the liver, because it allows L. monocytogenes to infect neighboring cells without being exposed to opsonization or recognition and killing by innate immune cells.
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Neutrophils remove bacterial and fungal pathogens through a process known as phagocytosis. Recognition of invading microbial pathogens is mediated by receptors present on the neutrophil surface, such as PRRs (e.g., TLRs) and opsonic receptors, which recognize host proteins that are deposited on the microbial surface.
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