Why phosphofructokinase is regarded as pacemaker of glycolysis?
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Phosphofructokinase is the most prominent regulatory enzyme in glycolysis, but it is not the only one. Hexokinase, the enzyme catalyzing the first step of glycolysis, is inhibited by its product, glucose 6-phosphate. ... In turn, the level of glucose 6-phosphate rises because it is in equilibrium with fructose 6-phosphate.
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