Write a note on classification of hormones based on mode of action.
Answers
Chemical Nature:-
(a) Steroid Hormones:
These are made up of lipids, which basically derived from cholesterol, e.g. Testosterone, Estrogen, Progesterone etc.
b) Amine Hormones:
These hormones are made up of amines. Amine hormone is derivative of the amino acid tyrosine.
e.g. T3, T4, epinephrine, norepinephrine.
(c) Peptide Hormones:
These hormones are made up of few amino acid residues only and present as simple linear chain.
e.g. Oxytocin and vasopressin both consist of only 9-amino acid residues only.
(d) Protein Hormones:
These hormones are also made amino acid residues which are much more in numbers. They represent primary, secondary and tertiary configuration.
e.g. Insulin, glucagon, STH etc.
(e) Glycoprotein Hormones:
These hormones are glycoprotein in nature. They are conjugated protein where carbohydrate groups are mannose, galactose, fucose etc.
e.g. LH, FSH, TSH etc.
(f) Eicosanoids Hormones:
The eicosanoids are small fatty acid derivatives with a variety of arachidonic acid.
e.g. Prostaglandins.
Category # 2. On the Basis of Mechanism of Action:
(a) Group I hormones:
These hormones bind to intracellular receptors to form hormone-receptor complexes (HRC), through which their biochemical functions are mediated. These hormones are lipophilic in nature and are derivatives of cholesterol (except T3 and T4).
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