Write a paragraph on discovery of leukemia in simple words.
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The early history of leukemia reaches back 200 years. In 1811, Peter Cullen defined a case of splenitis acutus with unexplainable milky blood. Alfred Velpeau defined the leukemia associated symptoms, and observed pus in the blood vessels (1825). Alfred Donne detected a maturation arrest of the white blood cells (1844). John Bennett named the disease leucocythemia, based on the microscopic accumulation of purulent leucocytes (1845).
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Discovery of leukemia.
Velpeau (1825), Donné (1844), Bennett (1845), Craigie (1845), Virchow (1845), and Fuller (1846), establish the possibility that sustained leukocytosis could occur in the absence of infection. It is discovered that leukemia originates in the bone marrow.
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