Write a short note on carcinogenic compounds
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⚽Several polycyclic aromatic compounds are toxic and carcinogenic.
⚽eg. Benzene is oxidized to an epoxide, benzopyrene, in liver Benzopyrene is converted into epoxydiol.
⚽These substances can react with DNA and induce mutation leading to uncontrolled growth of certain cells. In this way, they cause cancer in the body.
⚽Carcinogenic compounds are produced by incomplete combustion of tobacco, coal and petroleum. Hence tobacco, coal are called cancer causing substances (carcinogenic substances).
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Chemical carcinogens are agents that are capable of inducing cancer in humans or animals. Most of the many hundreds of chemical carcinogens known have been recognised as such as a result of tests in rats or mice.
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