Write about development of bone
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Bone development begins with the replacement of collagenous mesenchymal tissue by bone. Generally, bone is formed by endochondral or intramembranous ossification. Intramembranous ossification is essential in the bone such as skull, facial bones, and pelvis which MSCs directly differentiate to osteoblasts.
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Hi mate
ᴛʜᴇ ғᴏʀᴍᴀᴛɪᴏɴ ᴏғ ʙᴏɴᴇ ɪs ᴄᴀʟʟᴇᴅ ᴏssɪғɪᴄᴀᴛɪᴏɴ. ᴅᴜʀɪɴɢ ᴛʜᴇ ғᴇᴛᴀʟ sᴛᴀɢᴇ ᴏғ ᴅᴇᴠᴇʟᴏᴘᴍᴇɴᴛ ᴛʜɪs ᴏᴄᴄᴜʀs ʙʏ ᴛᴡᴏ ᴘʀᴏᴄᴇssᴇs: ɪɴᴛʀᴀᴍᴇᴍʙʀᴀɴᴏᴜs ᴏssɪғɪᴄᴀᴛɪᴏɴ ᴀɴᴅ ᴇɴᴅᴏᴄʜᴏɴᴅʀᴀʟ ᴏssɪғɪᴄᴀᴛɪᴏɴ. ᴇɴᴅᴏᴄʜᴏɴᴅʀᴀʟ ᴏssɪғɪᴄᴀᴛɪᴏɴ ᴏᴄᴄᴜʀs ɪɴ ʟᴏɴɢ ʙᴏɴᴇs ᴀɴᴅ ᴍᴏsᴛ ᴏᴛʜᴇʀ ʙᴏɴᴇs ɪɴ ᴛʜᴇ ʙᴏᴅʏ; ɪᴛ ɪɴᴠᴏʟᴠᴇs ᴛʜᴇ ᴅᴇᴠᴇʟᴏᴘᴍᴇɴᴛ ᴏғ ʙᴏɴᴇ ғʀᴏᴍ ᴄᴀʀᴛɪʟᴀɢᴇ.
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