Question

write mechanism of mannich reaction

Answer 1

The first step in the mechanism of Mannich Reaction is the formation of iminium ion from the reaction between fiormaldehyde and amine. Then, it reacts with acid to form amino methylated product after rearrangement. Ammonia or primary or secondary amines are used for the activation of formaldehyde.

Answer 2

The first step in the mechanism of Mannich Reaction is the formation of iminium ion from the reaction between fiormaldehyde and amine. Then, it reacts with acid to form amino methylated product after rearrangement. Ammonia or primary or secondary amines are used for the activation of formaldehyde.