Write the genotype of the normal parents producing haemophilic son
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Thalassemia and haemophilia are categorised as Mendelian disorders because these disorders are due to alteration in a single gene. Also, they are transmitted to offsprings through Mendelian principles of inheritance.
Symptoms and pattern of inheritance are given below:
(a) Thalassemia It is an autosomal linked recessive blood disorder characterised by defect in a, (3 or 8 chain resulting in abnormal Hb molecule. Symptom Anaemia
Inheritance Two mutant alleles (one from each parent) must be inherited for an individual to be affected, i.e. homozygous. Heterozygous are carriers and may pass the mutant allele to children.
Thalassemia and haemophilia are categorised as Mendelian disorders because these disorders are due to alteration in a single gene. Also, they are transmitted to offsprings through Mendelian principles of inheritance.
Symptoms and pattern of inheritance are given below:
(a) Thalassemia It is an autosomal linked recessive blood disorder characterised by defect in a, (3 or 8 chain resulting in abnormal Hb molecule. Symptom Anaemia
Inheritance Two mutant alleles (one from each parent) must be inherited for an individual to be affected, i.e. homozygous. Heterozygous are carriers and may pass the mutant allele to children.
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