Write two names of diseases, one by external factors and the other due to internal deficiency or irregularity.
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disease is a particular abnormal condition that negatively affects the structure or function of all or part of an organism, and that is not due to any immediate external injury.[1][2] Diseases are often known to be medical conditions that are associated with specific symptoms and signs.[1]‹See TfM›[failed verification] A disease may be caused by external factors such as pathogens or by internal dysfunctions. For example, internal dysfunctions of the immune system can produce a variety of different diseases, including various forms of immunodeficiency, hypersensitivity, allergies and autoimmune disorders.
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1) Malaria - mosquitoes
2) Down syndrome - genetic disorder
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