You are given a metaphase chromosome preparation (a slide) from an unknown organism that contains 12 chromosomes. Two that are clearly smaller than the rest appear identical in length and centromere placement. Describe all that you can about these chromosomes.
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Consider an animal cell in which motor proteins in the kinetochores normally pull the chromosomes along the kinetochore microtubules during mitosis.
Suppose, however, that during metaphase, this cell was treated with an inhibitor that blocks the function of the motor proteins in the kinetochore, but allows the kinetochore to remain attached to the spindle. The inhibitor has no effect on any other mitotic process, including the function of the nonkinetochore microtubules.
Will this cell elongate during mitosis? (yes or no?)
Will the sister chromatids separate from each other? (yes or no?)
Will the chromosomes move to the poles of the cell? (yes or no?)
Suppose, however, that during metaphase, this cell was treated with an inhibitor that blocks the function of the motor proteins in the kinetochore, but allows the kinetochore to remain attached to the spindle. The inhibitor has no effect on any other mitotic process, including the function of the nonkinetochore microtubules.
Will this cell elongate during mitosis? (yes or no?)
Will the sister chromatids separate from each other? (yes or no?)
Will the chromosomes move to the poles of the cell? (yes or no?)
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