Question

You developed a drug which inhibits Na±K+ATPase , which of the following situations will occur, please explain your reason. A) Decreased intracellular Na+ concentration B) Increased intracellular K+ concentration C) Increased Na+ Glucose co transport D) Decreased Na+ Glucose co transport?
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Answer 1

Explanation:

Since Na,K-ATPase is important for maintaining various cellular functions, its inhibition could result in diverse pathologic states. Inhibition of Na,K-ATPase causes high intracellular Na+ ion levels and subsequent increases in intracellular Ca2+ ion through the Na+/Ca2+ exchanger