(3) How does Catechol undergo Williamson's
Synthesis
CH2I2 & Naon?
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The Williamson ether synthesis is an organic reaction, forming an ether from an organohalide and a deprotonated alcohol (alkoxide). ... An example is the reaction of sodium ethoxide with chloroethane to form diethyl ether and sodium chloride: [Na]+[C2H5O]− + C2H5Cl → C2H5OC2H5 + [Na]+[Cl]
The Williamson ether synthesis is an SN2 reaction in which an alkoxide ion is a nucleophile that displaces a halide ion from an alkyl halide to give an ether. The reaction occurs with inversion of configuration at chiral centers and can be limited by possible competing elimination reactions.
The Williamson ether synthesis is a reaction that converts alcohols (R-OH) into ethers (R-O-R). The first step in this reaction is forming the conjugate base of the alcohol (called an alcoxide) by reacting the alcohol with sodium metal.
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The Williamson ether synthesis is an organic reaction, forming an ether from an organohalide and a deprotonated alcohol (alkoxide). This reaction was developed by Alexander Williamson in 1850. Typically it involves the reaction of an alkoxide ion with a primary alkyl halide via an SN2 reaction.
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