Question

4. For the following a-b, state whether the procedure could cause cells to lose growth control. Explain your reasoning in 1-2 sentences.

a) A copy of the gene for epidermal growth factor receptor (EGFR) that encodes a mutant, constitutively active receptor is introduced into a cell that carries two normal copies of the EGFR gene.



b) A normal erythropoietin (epo) cDNA (encodes a growth factor for erythroid stem cells) attached to a constitutive promoter is introduced into an erythroid stem cell that carries two normal copies of the erythropoietin gene.

Answer 1

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