A DNA sequence needed for coding a peptide is given below CAAGTAAATTGAGGACTC a) Write the complimentary mRNA coding sequence for this. b) Find out the amino acid sequence of the peptide chain . c) If a mutation causes a change in the sixth codon CTC TO CAC,it leads to Mendelian disorder. Identify the disease and write the specific characteristic of the disease.
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The given sequence of nucleotides in DNA strand is TAC AAA GGG TTT CAA CCC. Thus, the sequence of nucleotides in mRNA strand will be AUG UUU CCC AAA GUU GGG as mRNA has complementary sequence to that of DNA strand. There are six triplet codons in mRNA, hence it will code for six amino acids. Amino acid for AUG is methionine, for UUU is phenylalanine, for CCC is proline, for AAA is lysine, for GUU is valine and for GGG is glycine.
Thus, the amino acid sequnce in a protein formed will be Methionine, pherrylalanine, proline, lysine, valine, glycine.
Thus, the correct answer is option D.
Explanation:
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