Question

A female who has no prior history of thalassemia in her family marries a thalessemic man. If their son marries a carrier woman then what will be the probability of their grandson to be affected with thalessemia

Answer 1

Answer:

25%

Explanation:

Answer 2

The chance of the son to be affected of thalassemia will be 25%.

Explanation:

• Thalassemia is a genetic diseases.

• Its the disease where the person has the mutated gene of beta chain in the chromosome 11 of the affected person.

• The mutated gene is recessive, so the person having mutated gene in 1 chromosome is a carrier.

• The father is thalassemic whereas the mother is normal.

• So the son becomes a carrier by character.

• So if the carrier son marries a carrier daughter and the son is produced from this couple, then the chance of the grandson being thalassemic is 25%.

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