Question

A major problem with the computational assembly of dna sequence of complex eukaryotic genomes is the presence of

Answer 1

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Answer 2

A major problem with the computational assembly of the DNA sequence of complex eukaryotic genomes is the presence of introns.

• The primary issue with the human genome and the genomes of higher eukaryotes, in general, is that their genes frequently have introns that separate them and prevent them from showing up as continuous ORFs in the DNA sequence.
• A gene's exons, or coding sections, are separated by a substantial section of noncoding DNA called an intron.
• Since the coding portions of intron-containing genes are not continuous, they are also referred to as split or discontinuous genes.
• Only eukaryotic organisms have introns.

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