Question

A mutation in the carbohydrate recognition domain drives a phenotypic switch in the role of galectin-7 in prostate cancer.

Answer 1

The observation that galectin-7 (gal-7) is specifically expressed in mammary myoepithelial (basal) cells prompted us to investigate whether this protein is expressed in the basal cells of other tissues. Given that breast and prostate cancer have remarkable underlying …