Question

Define cooperativity in bioinorganic chemistry

Answer 1

Heya
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Cooperativity is the interaction process by which binding of a ligand to one site on a macromolecule (enzyme, receptor, etc.) influences binding at a second site, e.g. between the substrate binding sites of an allosteric enzyme.

Cooperative enzymes typically display a sigmoid (S-shaped) .

Hope this helps you.

Answer 2

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Cooperativity is the interaction process by which binding of a ligand to one site on a macromolecule (enzyme, receptor, etc.) influences binding at a second site, e.g. between the substrate binding sites of an allosteric enzyme.

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