define kolbe reaction
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The Kolbe reaction is an organic reaction used to convert a phenol to a hydroxy benzoic acid using carbon dioxide gas, a base, and acid work-up. The mechanism begins with deprotonation of the phenol by the base to form a phenoxide.
The Kolbe reaction is an organic reaction used to convert a phenol to a hydroxy benzoic acid using carbon dioxide gas, a base, and acid work-up. The mechanism begins with deprotonation of the phenol by the base to form a phenoxide.
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The Kolbe–Schmitt reaction or Kolbe process(named after Hermann Kolbe and Rudolf Schmitt) is a carboxylation chemical reactionthat proceeds by heating sodium phenoxide (the sodium salt of phenol) with carbon dioxide under pressure (100 atm, 125 °C), then treating the product with sulfuric acid. The final product is an aromatic hydroxy acidwhich is also known as salicylic acid (the precursor to aspirin).
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