Question

Describe Edward's syndrome​

Answer 1

Answer:

Edwards syndrome is marked by a low birth weight and certain abnormal features. These include a small, abnormally shaped head; a small jaw and mouth; clenched fists with overlapping fingers; and heart, lung, kidney, intestine, and stomach defects.

Answer 2

Edwards syndrome, also known as trisomy 18, is a genetic disorder caused by the presence of a third copy of all or part of chromosome 18. Many parts of the body are affected. Babies are often born small and have heart defects. Other features include a small head, small jaw, clenched fists with overlapping fingers, and severe intellectual disability.

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Specialty ➪ Medical genetics, pediatrics

Symptoms ➪ Small head, small jaw, clenched fists with overlapping fingers, profound intellectual disability

Complications ➪ Heart defects

Usual onset➪ Present at birth

Causes ➪Third copy of chromosome 18 (usually new mutation)

Risk factors ➪ Older mother

Diagnostic method ➪ Ultrasound, amniocentesis

Treatment ➪ Supportive care

Prognosis ➪ 5–10% survive past a year old

Frequency ➪ 1 per 5,000 births