Question

Difference between oncogene and tumour suprresour gene

Answer 1

Answer:

Oncogene

Oncogene1. Mutation in one of the two alleles is sufficient for activity as an oncogene and often act dominant to wild type.

Oncogene1. Mutation in one of the two alleles is sufficient for activity as an oncogene and often act dominant to wild type.2. Mutation often occurs in somatic tissues therefore not inherited

Oncogene1. Mutation in one of the two alleles is sufficient for activity as an oncogene and often act dominant to wild type.2. Mutation often occurs in somatic tissues therefore not inherited3. Conversion of protooncogene to oncogene is often a “gain of function” of protein that signals uncontrolled cell division.

Oncogene1. Mutation in one of the two alleles is sufficient for activity as an oncogene and often act dominant to wild type.2. Mutation often occurs in somatic tissues therefore not inherited3. Conversion of protooncogene to oncogene is often a “gain of function” of protein that signals uncontrolled cell division.4. Some tissue preference.

Oncogene1. Mutation in one of the two alleles is sufficient for activity as an oncogene and often act dominant to wild type.2. Mutation often occurs in somatic tissues therefore not inherited3. Conversion of protooncogene to oncogene is often a “gain of function” of protein that signals uncontrolled cell division.4. Some tissue preference.Tumor Suppressor Genes

Oncogene1. Mutation in one of the two alleles is sufficient for activity as an oncogene and often act dominant to wild type.2. Mutation often occurs in somatic tissues therefore not inherited3. Conversion of protooncogene to oncogene is often a “gain of function” of protein that signals uncontrolled cell division.4. Some tissue preference.Tumor Suppressor Genes1. Tumor suppressor gene malfunctioning is caused by mutations in both alleles or a mutation in one followed by a loss of or reduction to homozygosity in the second.

Oncogene1. Mutation in one of the two alleles is sufficient for activity as an oncogene and often act dominant to wild type.2. Mutation often occurs in somatic tissues therefore not inherited3. Conversion of protooncogene to oncogene is often a “gain of function” of protein that signals uncontrolled cell division.4. Some tissue preference.Tumor Suppressor Genes1. Tumor suppressor gene malfunctioning is caused by mutations in both alleles or a mutation in one followed by a loss of or reduction to homozygosity in the second.2. Mutation may occur in germ cell (can be inherited) or somatic cells.

Oncogene1. Mutation in one of the two alleles is sufficient for activity as an oncogene and often act dominant to wild type.2. Mutation often occurs in somatic tissues therefore not inherited3. Conversion of protooncogene to oncogene is often a “gain of function” of protein that signals uncontrolled cell division.4. Some tissue preference.Tumor Suppressor Genes1. Tumor suppressor gene malfunctioning is caused by mutations in both alleles or a mutation in one followed by a loss of or reduction to homozygosity in the second.2. Mutation may occur in germ cell (can be inherited) or somatic cells.3. ‘Loss of function’ mutation is the reason for tumor suppressor gene malfunctioning.

Oncogene1. Mutation in one of the two alleles is sufficient for activity as an oncogene and often act dominant to wild type.2. Mutation often occurs in somatic tissues therefore not inherited3. Conversion of protooncogene to oncogene is often a “gain of function” of protein that signals uncontrolled cell division.4. Some tissue preference.Tumor Suppressor Genes1. Tumor suppressor gene malfunctioning is caused by mutations in both alleles or a mutation in one followed by a loss of or reduction.