Explain the mechanism of aldol condensation
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Aldol condensation is an organic reaction in which an enolate ion reacts with carboxyl compound in order to form a β– hydroxyaldehyde or β– hydroxyketone.
1)Hydroxide functions as a base and therefore moves the acidic a-hydrogen producing the reactive enolate ion. This reaction can be seen as an acid-base reaction.
2) The aldehyde is attacked at the electrophilic carbonyl carbon by the nucleophilic enolate ion. This attack is a nucleophilic addition reaction and gives alkoxide intermediate.
3) The alkoxide deprotonates water molecule, thereby producing hydroxide and the β-hydroxyaldehyde.
1)Hydroxide functions as a base and therefore moves the acidic a-hydrogen producing the reactive enolate ion. This reaction can be seen as an acid-base reaction.
2) The aldehyde is attacked at the electrophilic carbonyl carbon by the nucleophilic enolate ion. This attack is a nucleophilic addition reaction and gives alkoxide intermediate.
3) The alkoxide deprotonates water molecule, thereby producing hydroxide and the β-hydroxyaldehyde.
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