Chemistry, asked by ibbitahir826, 1 year ago

How will you selectively protect phenolic oh and cooh group of salicylic acid?

Answers

Answered by SuperstarPiyush

2

Wheras aspirin is obtained by treating salicylic acid with acetylating agents leading ... But to make “acetic salicylic anhydride” you would have to first protect the phenol group so that it ...

Phenolic OH is more reactivetowards acetic anhydride than acidic OH because ... density is distributed among two Oxygens of carboxylic group (Lower nucleophilicity).

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