Most generally recommended nsaid is diclofenac when it is consumed at prescribed concentration and for a shorter term it is safe, principally upon their consistent utilization and higher dosage, it is accounted for to cause hepatotoxicity, renal toxicity and gastrointestinal toxicity
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Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) of the phenylacetic acid class with anti-inflammatory, analgesic, and antipyretic properties. Contrary to the action of many traditional NSAIDs, diclofenac inhibits cyclooxygenase (COX)-2 enzyme with greater potency than it does COX-1. Similar to other NSAIDs, diclofenac is associated with serious dose-dependent gastrointestinal, cardiovascular, and renal adverse effects.
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