Question

On which chromosome 2 closely linked genes hba1 and hba2 are mutated which causes alpha thalassemia

Answer 1

The HBA2 gene provides instructions for making a protein called alpha-globin. This protein is also produced from a nearly identical gene called HBA1. These two alpha-globin genes are located close together in a region of chromosome 16 known as the alpha-globin locus.

Answer 2

Alpha thalassemia is a blood disorder that reduces the production of hemoglobin. ... Affected individuals also have a shortage of red blood cells (anemia), which can cause pale skin, weakness, fatigue, and more serious complications. Two types of alpha thalassemia can cause health problems.