Question:-
Describe briefly the followings:-
(a) Origin of replication
(b) Bioreactors
(c) Downstream processing
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Answers
@) Origin of replication is defined as the DNA sequence in a genome from where replication initiates. The initiation of replication can be either uni-directional or bi-directional. A protein complex recognizes the 'on' site, unwinds the two strands, and initiates the copying of the DNA.
b) Bioreactor are vessels in which raw materials are biologically converted into specific products using microbial, plant or human cells. It provides optimal conditions for achieving the desired product by providing optimum growth conditions, pH, substrate salts, vitamins, oxygen, etc.
c)Downstream processing.are the series of processes which a genetically modified product undergoes before it is ready to be marketed. It generally involves processes like separation and purification..
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