Simmond's disease is related to which gland ?
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It is realted to pituitary gland..
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this may be your perfect answer i have got this from my textbook
normally it related to pituitary gland
and the more information is up to you
Our pituitary gland is the 'master gland,' the driving part of our endocrine system. In this lesson, we'll look at what happens when the anterior pituitary gland doesn't work properly and distinguish between two resulting conditions called Simmonds' disease and Sheehan's syndrome.
Introduction to Panhypopituitarism
Drowsy driving can be disastrous. Our pituitary gland serves as the 'driver' of our endocrine system by secreting hormones essential to maintaining homeostasis. Simmonds' disease and Sheehan's syndrome are conditions that occur when the pituitary is 'asleep at the wheel,' failing to make hormones vital to keeping our body's systems in balance.
Let's tackle this topic by reviewing what we know about the pituitary gland. The pituitary gland, sometimes referred to as the body's master gland, is a pea-sized gland that functions as a control center for the body's endocrine system. It connects the nervous and endocrine systems by receiving signals from the brain and stimulating many hormonal pathways.
The pituitary gland is divided into two portions: the anterior and the posterior. Each part makes different hormones. Because of the number of hormones and the wide ranges of their effects, this lesson will focus on the anterior portion. Let's recap the major hormones this part makes and what they do.
Name of HormoneAbbreviationSite of ActionPrimary Actionthyroid stimulating hormoneTSHthyroidrelease of thyroxinegrowth hormoneGHall cellsgrowthfollicle stimulating hormoneFSHreproductive systemegg development (women) sperm production (men)luteinizing hormoneLHreproductive systemsex hormone production (both sexes)adrenocorticotropic hormoneACTHadrenal glandbalance of blood glucose levels, stress mediation, sex characteristics, sodium and water balance
Note that these hormones have something in common. They all stimulate a reaction in other cells, glands, or organs.
Panhypopituitarism results when the production of the anterior hormones is either insufficient or absent. Pan refers to all and is used when the majority of these hormones are absent.
In adults, this condition is usually caused by damage due to surgery or radiation. Other causes include stroke, infection or inflammation, tumors (called pituitary adenomas), attack by the body's own immune system, or injury. Children sometimes develop panhypopituitarism either congenitally or due to asphyxia during childbirth.
Simmonds' Disease and Sheehan's Syndrome
Panhypopituitarism is commonly called Simmonds' disease after the physician who first described it. It's also called pituitary cachexia. Cachexia means wasting. This is because Simmonds' disease results in atrophy (shrinking and reduced function) of the cells and organs that are normally stimulated by pituitary hormones. This makes sense - if the body's not using it, it's going to lose it.
The physical symptoms of Simmonds' disease depend on the cause. For example, if the disease is caused by a tumor and presses on the optic nerve and surrounding brain structures, then headaches and blurred vision are common.
Most of the symptoms of Simmonds', however, stem from the lack of pituitary hormones, and the atrophy that follows. If you know the organs and glands that the pituitary stimulates, you can probably guess the symptoms. Let's go back to the table we used earlier and add another column to it.
Name of HormoneAbbreviationSite of ActionPrimary ActionSymptomthyroid stimulating hormoneTSHthyroidrelease of thyroxineslow heartbeat, drop in metabolism, and weight gaingrowth hormoneGHall cellsgrowthweakness, stunted growth in children, and obesity in adultsfollicle stimulating hormoneFSHreproductive systemegg development (women) sperm production (men)infertility; menstruation problems in womenluteinizing hormoneLHreproductive systemsex hormone productionreduced sex characteristics; infertilityadrenocorticotropic hormoneACTHadrenal glandbalance of blood glucose levels, stress mediation, sex characteristics, sodium and water balancedrop in energy, low blood sugar, low blood pressure, and poor response to stress
normally it related to pituitary gland
and the more information is up to you
Our pituitary gland is the 'master gland,' the driving part of our endocrine system. In this lesson, we'll look at what happens when the anterior pituitary gland doesn't work properly and distinguish between two resulting conditions called Simmonds' disease and Sheehan's syndrome.
Introduction to Panhypopituitarism
Drowsy driving can be disastrous. Our pituitary gland serves as the 'driver' of our endocrine system by secreting hormones essential to maintaining homeostasis. Simmonds' disease and Sheehan's syndrome are conditions that occur when the pituitary is 'asleep at the wheel,' failing to make hormones vital to keeping our body's systems in balance.
Let's tackle this topic by reviewing what we know about the pituitary gland. The pituitary gland, sometimes referred to as the body's master gland, is a pea-sized gland that functions as a control center for the body's endocrine system. It connects the nervous and endocrine systems by receiving signals from the brain and stimulating many hormonal pathways.
The pituitary gland is divided into two portions: the anterior and the posterior. Each part makes different hormones. Because of the number of hormones and the wide ranges of their effects, this lesson will focus on the anterior portion. Let's recap the major hormones this part makes and what they do.
Name of HormoneAbbreviationSite of ActionPrimary Actionthyroid stimulating hormoneTSHthyroidrelease of thyroxinegrowth hormoneGHall cellsgrowthfollicle stimulating hormoneFSHreproductive systemegg development (women) sperm production (men)luteinizing hormoneLHreproductive systemsex hormone production (both sexes)adrenocorticotropic hormoneACTHadrenal glandbalance of blood glucose levels, stress mediation, sex characteristics, sodium and water balance
Note that these hormones have something in common. They all stimulate a reaction in other cells, glands, or organs.
Panhypopituitarism results when the production of the anterior hormones is either insufficient or absent. Pan refers to all and is used when the majority of these hormones are absent.
In adults, this condition is usually caused by damage due to surgery or radiation. Other causes include stroke, infection or inflammation, tumors (called pituitary adenomas), attack by the body's own immune system, or injury. Children sometimes develop panhypopituitarism either congenitally or due to asphyxia during childbirth.
Simmonds' Disease and Sheehan's Syndrome
Panhypopituitarism is commonly called Simmonds' disease after the physician who first described it. It's also called pituitary cachexia. Cachexia means wasting. This is because Simmonds' disease results in atrophy (shrinking and reduced function) of the cells and organs that are normally stimulated by pituitary hormones. This makes sense - if the body's not using it, it's going to lose it.
The physical symptoms of Simmonds' disease depend on the cause. For example, if the disease is caused by a tumor and presses on the optic nerve and surrounding brain structures, then headaches and blurred vision are common.
Most of the symptoms of Simmonds', however, stem from the lack of pituitary hormones, and the atrophy that follows. If you know the organs and glands that the pituitary stimulates, you can probably guess the symptoms. Let's go back to the table we used earlier and add another column to it.
Name of HormoneAbbreviationSite of ActionPrimary ActionSymptomthyroid stimulating hormoneTSHthyroidrelease of thyroxineslow heartbeat, drop in metabolism, and weight gaingrowth hormoneGHall cellsgrowthweakness, stunted growth in children, and obesity in adultsfollicle stimulating hormoneFSHreproductive systemegg development (women) sperm production (men)infertility; menstruation problems in womenluteinizing hormoneLHreproductive systemsex hormone productionreduced sex characteristics; infertilityadrenocorticotropic hormoneACTHadrenal glandbalance of blood glucose levels, stress mediation, sex characteristics, sodium and water balancedrop in energy, low blood sugar, low blood pressure, and poor response to stress
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