what is itai itai disease ?
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Itai-itai disease is caused by cadmium (Cd) exposure, produced as a result of human activities related to industrialisation, and this condition was first recognised in Japan in the 1960s. 1 2. Itai-itai disease is characterised by osteomalaecia with severe bone pain and is associated with renal tubular dysfunction.
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Itai-itai diseases was the name given to the mass cadmium poisoning of Toyama Prefecture, Japan, starting around 1912. The term "itai-itaidisease" was coined by locals for the severe pains people with the condition felt in the spine and joints.
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