Which of theses statements about proximal convoluted tubule is/are true?
I. it is lined by simple columnar brush border epithelium which increases the surface area for reabsorption.
II Nearly all of the essential nutrients and 70%-80% of electrolytes and water are reabsorbed by this segment.
III. It selectively secretes hydrogen ions, ammonia and potassium ions into the filtrate.
IV. It is the most convoluted part of the nephron and is present in the medullary region of the kidney.
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