Why activity of enzyme is reduced when substrate concentration exceeds the enzyme level?
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thus competitive inhibitors increase the Km of a reaction because they increase the concentration of substrate required to substrate the enzyme.
however they don't change Vmax itself. in the case of certain enzymes, high concentration of either substrate or the product can be inhibitory.
however they don't change Vmax itself. in the case of certain enzymes, high concentration of either substrate or the product can be inhibitory.
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